Description

1-Boc-3-Carboxymethylindole/2-(1-(tert-Butoxycarbonyl)-1H-Indol-3-Yl)Acetic Acid is a high-purity, protected indole derivative that serves as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise molecular scaffolds for the development of complex pharmaceuticals and bioactive molecules. It is primarily utilized in the synthesis of drug candidates, particularly in medicinal chemistry for creating indole-based compounds with potential therapeutic applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Peptidomimetic Synthesis: Employed in the construction of indole-containing peptidomimetics and constrained amino acid analogs.
• Agrochemical Development: Serves as an intermediate in the research and production of advanced crop protection agents and plant growth regulators.
• Material Science: Potential use in the synthesis of specialty polymers and organic electronic materials due to its conjugated indole core.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting synthetic methodology development.

Basic Information

Product Name	1-Boc-3-Carboxymethylindole/2-(1-(tert-Butoxycarbonyl)-1H-Indol-3-Yl)Acetic Acid
CAS No.	128550-08-3
Molecular Formula	C₁₆H₁₉NO₄
Molecular Weight	289.33 g/mol
Synonyms	2-(1-[(tert-Butoxy)carbonyl]-1H-indol-3-yl)acetic acid; 1-Boc-3-indolylacetic acid; 1-(tert-Butoxycarbonyl)-3-indoleacetic acid; 2-[1-(tert-Butoxycarbonyl)indol-3-yl]acetic acid; tert-Butyl 3-(carboxymethyl)indole-1-carboxylate; 1-Boc-indole-3-acetic acid; BOC-Indole-3-Acetic Acid; N-Boc-3-indolylacetic acid
EINECS	Contact for details

Quality Control

Our 1-Boc-3-Carboxymethylindole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.