Description

(S)-2-Amino-1-(4-Chlorophenyl)Ethanol CAS NO 128535-89-7 is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis. Its defined stereochemistry and functional groups make it a critical precursor for the development of active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel, optically active compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of β-adrenergic blocking agents (β-blockers) and other cardiovascular or central nervous system (CNS) active drugs.
• Agrochemical Synthesis: Used in the production of chiral herbicides, fungicides, and plant growth regulators where specific stereochemistry enhances efficacy and reduces environmental impact.
• Asymmetric Catalyst Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in metal-catalyzed asymmetric reactions, such as hydrogenation or epoxidation.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals and flavors & fragrances requiring precise stereochemical control.
• Academic & Industrial Research: Utilized in medicinal chemistry programs for structure-activity relationship (SAR) studies and the development of new chemical entities.

Basic Information

Product Name	(S)-2-Amino-1-(4-Chlorophenyl)Ethanol
CAS No.	128535-89-7
Molecular Formula	C8H10ClNO
Molecular Weight	171.62 g/mol
Synonyms	(S)-1-(4-Chlorophenyl)-2-aminoethanol; (S)-2-Amino-1-(4-chlorophenyl)ethan-1-ol; (S)-(-)-4-Chloro-α-[(methylamino)methyl]benzyl alcohol; (S)-4-Chlorophenylglycinol; (S)-p-Chlorophenylglycinol; (S)-2-Amino-2-(4-chlorophenyl)ethanol; (1S)-2-Amino-1-(4-chlorophenyl)ethanol; L-4-Chlorophenylglycinol
EINECS	Contact for details

Quality Control

Our (S)-2-Amino-1-(4-Chlorophenyl)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.