Description

4-[(1R)-1-Hydroxy-2-[4-(4-Hydroxyphenyl)Butylamino]Ethyl]Benzene-1,2-Diol is a high-purity chiral compound of significant interest in advanced pharmaceutical research and development. Its molecular structure, featuring multiple phenolic hydroxyl groups and a specific (R)-configuration, makes it a valuable synthetic intermediate and a potential pharmacophore for novel therapeutics. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel adrenergic receptor agonists or other bioactive molecules targeting the central nervous system.
• Biochemical Research: Used as a reference standard or probe in studies of catecholamine pathways, enzyme inhibition, or receptor binding assays.
• Asymmetric Synthesis: Serves as a chiral precursor or template for the development of enantiomerically pure compounds in medicinal chemistry.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for potential active pharmaceutical ingredients (APIs).
• Analytical Standard: Provides a high-purity benchmark for quality control and method development in analytical laboratories (HPLC, LC-MS).

Basic Information

Product Name	4-[(1R)-1-Hydroxy-2-[4-(4-Hydroxyphenyl)Butylamino]Ethyl]Benzene-1,2-Diol
CAS No.	128470-16-6
Molecular Formula	C18H23NO4
Molecular Weight	317.38 g/mol
Synonyms	(R)-Denopamine; (R)-(-)-Denopamine; (-)-Denopamine; (R)-1-(p-Hydroxyphenoxy)-2-[[4-(p-hydroxyphenyl)butyl]amino]ethanol; (R)-4-[1-Hydroxy-2-[[4-(4-hydroxyphenyl)butyl]amino]ethyl]-1,2-benzenediol; (R)-TA-064; L-Denopamine; (R)-(-)-TA-064; 1,2-Benzenediol, 4-[(1R)-1-hydroxy-2-[[4-(4-hydroxyphenyl)butyl]amino]ethyl]-
EINECS	Contact for details

Quality Control

Our 4-[(1R)-1-Hydroxy-2-[4-(4-Hydroxyphenyl)Butylamino]Ethyl]Benzene-1,2-Diol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets exacting research-grade specifications. A detailed Certificate of Analysis (COA) confirming identity, purity, and enantiomeric excess is provided with every shipment to guarantee reproducible results for your critical R&D work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider sealing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% (R-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.