Description

(Z)-2-(2-Aminothiazole-4-Yl-)-2-Trityloxyimino Acetic Acid is a key advanced pharmaceutical intermediate characterized by its unique trityl-protected oxyimino acetic acid moiety. This compound is critical for ensuring the stability and reactivity of the final active pharmaceutical ingredient during complex synthesis. It is primarily utilized by manufacturers in the pharmaceutical industry for the production of advanced cephalosporin antibiotics, where its high purity and consistent quality are essential for regulatory compliance and therapeutic efficacy.

Application

• Key Intermediate for Cephalosporin Synthesis: Serves as a crucial building block in the manufacturing of third and fourth-generation cephalosporin antibiotics.
• Pharmaceutical Research & Development: Used in the R&D of new β-lactam antibiotics and related antimicrobial agents.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the final chemical synthesis steps for producing bulk APIs under GMP conditions.
• Process Chemistry & Scale-up: Integral to process optimization and commercial-scale production runs in fine chemical plants.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control laboratories.

Basic Information

Product Name	(Z)-2-(2-Aminothiazole-4-Yl-)-2-Trityloxyimino Acetic Acid
CAS No.	128438-01-7
Molecular Formula	C24H19N3O3S
Molecular Weight	429.49 g/mol
Synonyms	(Z)-2-(2-Aminothiazol-4-yl)-2-[(triphenylmethoxy)imino]acetic Acid; 2-(2-Aminothiazol-4-yl)-2-[(triphenylmethoxy)imino]acetic Acid (Z)-isomer; 2-(2-Aminothiazol-4-yl)-2-(trityloxyimino)acetic Acid; ATTA; 7-ACA Side Chain Intermediate; Trityl-Protected AT Acid
EINECS	Contact for details

Quality Control

Our production of (Z)-2-(2-Aminothiazole-4-Yl-)-2-Trityloxyimino Acetic Acid adheres to stringent quality management systems. The product undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and conformity with customer specifications. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing all critical quality attributes. We support manufacturing under quality standards appropriate for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.2%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.