Description

1-Ethyl-1H-Indole-3-Carbonitrile is a versatile indole-based nitrile building block of significant importance in advanced organic synthesis. Its molecular structure makes it a critical precursor for the development of complex heterocyclic compounds and active pharmaceutical ingredients (APIs). This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop novel compounds with specific biological or functional properties.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the indole scaffold's bioactivity.
• Material Science Precursor: Acts as a building block for organic electronic materials, dyes, and photoactive compounds.
• Academic & R&D: Employed in university and corporate research laboratories for method development and exploring new chemical spaces in heterocyclic chemistry.
• Ligand Synthesis: Useful for creating specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorescent Probe Development: The indole-nitril structure can be utilized to create fluorescent markers for biochemical sensing and imaging.

Basic Information

Product Name	1-Ethyl-1H-Indole-3-Carbonitrile
CAS No.	128200-45-3
Molecular Formula	C11H10N2
Molecular Weight	170.21 g/mol
Synonyms	1-Ethylindole-3-carbonitrile; 3-Cyano-1-ethylindole; 1-Ethyl-1H-indole-3-carbonitrile; 3-Cyano-1-ethyl-1H-indole; 1-Ethyl-3-cyanoindole; 1-Ethyl-3-indolecarbonitrile; 3-(Cyano)-1-ethylindole; 128200-45-3
EINECS	Contact for details

Quality Control

Our 1-Ethyl-1H-Indole-3-Carbonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.