Description

6-Hydroxy-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid Ethyl Ester Hydrochloride is a high-purity, synthetically valuable heterocyclic building block. This compound is crucial for pharmaceutical research and development, serving as a key intermediate in the synthesis of complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry and process development for new drug candidates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly those targeting neurological and cardiovascular systems.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis Building Block: Employed in the construction of more complex tetrahydroisoquinoline derivatives and fused heterocyclic systems.
• Process Chemistry Development: Serves as a reference standard and starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Utilized in universities and research institutes for studying organic reaction mechanisms and developing novel synthetic methodologies.

Basic Information

Product Name	6-Hydroxy-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid Ethyl Ester Hydrochloride
CAS No.	128073-50-7
Molecular Formula	C₁₂H₁₅NO₃·HCl
Molecular Weight	257.71 g/mol
Synonyms	Ethyl 6-Hydroxy-1,2,3,4-Tetrahydroisoquinoline-1-Carboxylate Hydrochloride; 1,2,3,4-Tetrahydro-6-hydroxy-1-isoquinolinecarboxylic Acid Ethyl Ester Hydrochloride; 6-Hydroxy-THIQ-1-COOEt·HCl; 6-Hydroxy-1,2,3,4-tetrahydro-1-isoquinolinecarboxylic Acid Ethyl Ester Hydrochloride; 6-Hydroxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic Acid Ethyl Ester Hydrochloride Salt
EINECS	Contact for details

Quality Control

Our 6-Hydroxy-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid Ethyl Ester Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.