Description

[2H9]-1-Aminopyrene CAS NO 128008-86-6 is a deuterium-labeled derivative of 1-aminopyrene, a key polycyclic aromatic hydrocarbon (PAH) metabolite. This stable isotope-labeled compound is essential for use as an internal standard in mass spectrometry, enabling precise quantification and eliminating matrix effects. It is critically needed by analytical laboratories and researchers in environmental monitoring, occupational health, and toxicology studies for the accurate analysis of PAH exposure and metabolic pathways.

Application

• Internal Standard for LC-MS/MS and GC-MS: Primary application for the quantitative analysis of 1-aminopyrene and related PAH metabolites in complex biological and environmental matrices.
• Biomonitoring and Exposure Assessment: Used in human biomonitoring studies to accurately measure occupational or environmental exposure to pyrene and other PAHs through urine or blood analysis.
• Metabolic Pathway Research: Serves as a tracer in in vitro and in vivo studies to investigate the enzymatic metabolism and detoxification pathways of polycyclic aromatic hydrocarbons.
• Method Development and Validation: Critical for developing, optimizing, and validating highly sensitive and specific analytical methods in accredited testing laboratories.
• Environmental Fate Studies: Employed in research tracking the degradation, transformation, and bioaccumulation of PAHs in ecosystems.
• Pharmaceutical Impurity Profiling: Can be utilized in trace analysis for impurity identification and quantification in pharmaceutical products where PAHs are potential contaminants.
• Quality Control Reference Material: Acts as a certified reference material (CRM) or high-purity standard for ensuring data accuracy and compliance in analytical testing.

Basic Information

Product Name	[2H9]-1-Aminopyrene
CAS No.	128008-86-6
Molecular Formula	C16H2D9N
Molecular Weight	~223.31 g/mol
Synonyms	1-Aminopyrene-d9; Deuterated 1-Aminopyrene; 1-AP-d9; 1-Amino[2H9]pyrene; Perdeuterated 1-Aminopyrene; 1-Pyrenamine-d9; Internal Standard for 1-Aminopyrene; PAH Metabolite Standard-d9
EINECS	Contact for details

Quality Control

Every batch of [2H9]-1-Aminopyrene is produced and analyzed under strict quality management protocols. We guarantee high chemical and isotopic purity through advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA), detailing batch-specific purity, isotopic enrichment, and solvent content, is provided with each shipment to support your GLP and ISO 17025 compliant workflows.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C (refrigerated) for long-term stability. The product is light-sensitive and should be handled under appropriate conditions to prevent photodegradation. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to brown solid or solution
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98% (Chemical Purity)
Isotopic Enrichment	≥98 atom % D
Assay (by HPLC)	95 - 105% of stated concentration (for solutions)
Solvent Content (Residual Solvent)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.