Description

3-Hydroxyisoscopoletin is a naturally occurring coumarin derivative with significant biological activity. This compound matters as a key intermediate and reference standard in pharmaceutical research and development, particularly for its potential anti-inflammatory and antioxidant properties. It is needed by researchers and manufacturers in the pharmaceutical, nutraceutical, and fine chemical industries for drug discovery, analytical method development, and the synthesis of more complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and probe in studies investigating oxidative stress, inflammation pathways, and enzyme inhibition.
• Natural Product Isolation & Analysis: Acts as a marker compound for the quality control and standardization of plant extracts and herbal medicines containing coumarins.
• Cosmeceutical Development: Explored for incorporation into advanced skincare formulations targeting photoaging and inflammation due to its antioxidant profile.
• Academic Research: Employed in universities and research institutes for pharmacological screening and structure-activity relationship (SAR) studies of coumarin analogs.

Basic Information

Product Name	3-Hydroxyisoscopoletin
CAS No.	127861-48-7
Molecular Formula	C10H8O5
Molecular Weight	208.17 g/mol
Synonyms	3-Hydroxyisoscopoletin; 6,7-Dihydroxy-8-methoxycoumarin; 8-Methoxyesculetin; 6,7-Dihydroxy-8-methoxy-2H-1-benzopyran-2-one; Isoscopoletin 6,7-diol; 3-Hydroxy-6,7-dimethoxycoumarin (related isomer); Coumarin derivative 127861-48-7
EINECS	Contact for details

Quality Control

Our 3-Hydroxyisoscopoletin is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.