Description

5-Bromo-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole is a high-value, heterocyclic organic compound featuring a fused indole and tetrahydropyridine scaffold. This molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile building block in modern synthetic chemistry. It is primarily sought after by research institutions and chemical manufacturers engaged in the development of novel bioactive molecules, particularly within the central nervous system (CNS) therapeutic area. The compound's unique structure facilitates the synthesis of complex pharmacophores targeting specific neurological pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting serotonin and dopamine receptors for CNS disorders.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities in academic and industrial R&D.
• Biochemical Tool Compound: Used in pharmacological assays and as a reference standard to study receptor binding and enzyme inhibition mechanisms.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to construct more elaborate heterocyclic systems due to its reactive bromine and nitrogen-containing rings.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents with specific biological activity.

Basic Information

Product Name	5-Bromo-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole
CAS No.	127792-80-7
Molecular Formula	C13H13BrN2
Molecular Weight	277.16 g/mol
Synonyms	5-Bromo-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole; 5-Bromo-3-(1,2,3,6-tetrahydro-4-pyridinyl)indole; 5-Bromo-3-(1,2,3,6-tetrahydro-4-pyridyl)-1H-indole; 5-Bromo-3-(1,2,3,6-tetrahydro-4-pyridyl)indole; 5-Bromo-3-(4-piperidinyl)-1H-indole (tautomer form); 5-Bromo-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole; 127792-80-7
EINECS	Contact for details

Quality Control

Every batch of our 5-Bromo-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting key parameters such as assay purity and impurity profiles. Our commitment to cGMP principles and analytical rigor guarantees a reliable supply of this high-purity intermediate.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.