Description

3-Thiophenecarbonitrile, 2-Chloro- is a versatile halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its dual functionality, where the chloro substituent offers a site for further functionalization and the nitrile group can be transformed into various other functional groups. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, particularly in the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the thiophene scaffold's bioactivity.
• Material Science Research: Serves as a monomer or building block for creating conjugated polymers and organic electronic materials like OLEDs and organic semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions, which are fundamental in modern synthetic chemistry.
• Chemical Biology Probes: Utilized to develop molecular probes for studying biological processes and enzyme mechanisms.

Basic Information

Product Name	3-Thiophenecarbonitrile, 2-Chloro-
CAS No.	127667-02-1
Molecular Formula	C5H2ClNS
Molecular Weight	143.59 g/mol
Synonyms	2-Chloro-3-cyanothiophene; 2-Chlorothiophene-3-carbonitrile; 2-Chloro-3-thiophenecarbonitrile; 3-Cyano-2-chlorothiophene; 2-Chloro-3-thiophenenitrile; 2-Chloro-3-thienylcarbonitrile; 2-Chloro-3-thienonitrile
EINECS	Contact for details

Quality Control

Our 3-Thiophenecarbonitrile, 2-Chloro- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of our global pharmaceutical and fine chemical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.