Description

Thiophene, 2,3-Dihydro-5-Methyl-2-(1-Methylethyl)-, 1,1-Dioxide (9Ci) is a specialized, high-purity sulfone derivative of a dihydrothiophene, identified by CAS number 127649-99-4. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis, valued for its unique sulfone moiety and structural complexity. It is primarily sought by research institutions, fine chemical manufacturers, and pharmaceutical R&D departments engaged in developing novel active ingredients and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those requiring a functionalized dihydrothiophene sulfone scaffold.
• Organic Synthesis Building Block: Used in advanced organic reactions, including cross-coupling and cyclization, to construct more complex heterocyclic systems.
• Agrochemical Research: Employed in the development of new generation pesticides and herbicides where the sulfone group imparts specific biological activity.
• Material Science: Investigated as a monomer or additive for creating specialized polymers with specific electronic or thermal properties.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing novel ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Item	Detail
Product Name	Thiophene, 2,3-Dihydro-5-Methyl-2-(1-Methylethyl)-, 1,1-Dioxide (9Ci)
CAS No.	127649-99-4
Molecular Formula	C8H14O2S
Molecular Weight	174.26 g/mol
Synonyms	5-Methyl-2-(1-methylethyl)-2,3-dihydrothiophene 1,1-dioxide; 2-Isopropyl-5-methyl-2,3-dihydrothiophene 1,1-dioxide; 2,3-Dihydro-5-methyl-2-(propan-2-yl)thiophene 1,1-dioxide; 2-(1-Methylethyl)-2,3-dihydro-5-methylthiophene 1,1-dioxide; 2-Isopropyl-5-methyl-2,5-dihydrothiophene 1,1-dioxide; 2,3-Dihydro-5-methyl-2-isopropylthiophene 1,1-dioxide
EINECS	Contact for details

Quality Control

Our production of Thiophene, 2,3-Dihydro-5-Methyl-2-(1-Methylethyl)-, 1,1-Dioxide adheres to stringent quality protocols. Each batch is analyzed using advanced chromatographic and spectroscopic techniques to ensure high chemical purity and structural integrity. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment, supporting its use in cGMP-compliant pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.