Description

Thiophene, 2,3-Dihydro-5-Methyl-2-(1-Methylethyl)-, 1-Oxide, cis- (9Ci) is a specialized, high-purity organosulfur compound characterized by its cis-configuration and sulfoxide functional group. This compound matters as a valuable chiral building block and intermediate in advanced organic synthesis, offering precise stereochemical control for the development of complex molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced material science applications.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting sulfur-containing heterocycles.
• Agrochemical Research: Used in the development and production of advanced pesticides and herbicides where the thiophene sulfoxide moiety imparts specific biological activity.
• Organic Synthesis Building Block: Employed in asymmetric synthesis and catalysis research as a versatile precursor for constructing complex molecular architectures.
• Material Science Precursor: Investigated for use in the synthesis of specialized polymers, ligands for metal complexes, and advanced electronic materials.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory submissions in the chemical and pharmaceutical industries.

Basic Information

Product Name	Thiophene, 2,3-Dihydro-5-Methyl-2-(1-Methylethyl)-, 1-Oxide, cis- (9Ci)
CAS No.	127632-12-6
Molecular Formula	C8H14OS
Molecular Weight	158.26 g/mol
Synonyms	cis-5-Methyl-2-(1-methylethyl)-2,3-dihydrothiophene 1-Oxide; cis-2-Isopropyl-5-methyl-2,3-dihydrothiophene 1-Oxide; 2,3-Dihydro-5-methyl-2-(1-methylethyl)thiophene 1-Oxide, cis-; cis-2-Isopropyl-5-methyl-2,3-dihydrothiophene S-oxide; (2R,3S)- or (2S,3R)-2-Isopropyl-5-methyl-2,3-dihydrothiophene 1-Oxide (relative stereochemistry); Dihydrothiophene sulfoxide derivative
EINECS	Contact for details

Quality Control

Our Thiophene, 2,3-Dihydro-5-Methyl-2-(1-Methylethyl)-, 1-Oxide, cis- (9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization using techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen or argon) to preserve stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Typical 98-99%)
Chiral Purity (Chiral HPLC)	≥ 98.0% de (Typical)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.