Description

1-(Chloromethyl)-3,4-Dihydroisoquinoline, Hydrochloride is a versatile and reactive organic salt, primarily serving as a key synthetic intermediate in advanced pharmaceutical and fine chemical manufacturing. Its value lies in the chloromethyl and dihydroisoquinoline moieties, which enable efficient construction of complex nitrogen-containing heterocycles. This compound is essential for researchers and production chemists in the pharmaceutical, agrochemical, and material science industries who require high-purity building blocks for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential therapeutic agents, particularly those targeting the central nervous system (CNS).
• Alkaloid Synthesis: Used in the construction of complex isoquinoline and tetrahydroisoquinoline alkaloid analogs for biological screening.
• Agrochemical Research: Serves as a precursor in the development of novel pesticides and herbicides with specific modes of action.
• Ligand and Catalyst Development: Employed in the preparation of specialized nitrogen-donor ligands for catalytic systems.
• Material Science: Investigated as a monomer or functionalizing agent for creating polymers with specific electronic or binding properties.
• Chemical Biology Probes: Utilized to develop molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	1-(Chloromethyl)-3,4-Dihydroisoquinoline, Hydrochloride
CAS No.	127606-02-4
Molecular Formula	C10H11Cl2N
Molecular Weight	216.11 g/mol
Synonyms	1-(Chloromethyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride; 3,4-Dihydro-1-(chloromethyl)isoquinoline hydrochloride; 1,2,3,4-Tetrahydro-1-(chloromethyl)isoquinoline HCl; 1-Chloromethyl-3,4-dihydroisoquinoline HCl; 1-(Chloromethyl)-3,4-dihydroisoquinoline HCl salt; 1-(Chloromethyl)-1,2,3,4-tetrahydroisoquinoline HCl; Isoquinoline, 1-(chloromethyl)-3,4-dihydro-, hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(Chloromethyl)-3,4-Dihydroisoquinoline, Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.