Description

1H-2-Oxa-7A-Azacyclopent[Cd]Inden-1-One, 4-Ethylidene-2A,3,4,6,7,7B-Hexahydro-3-[(Trimethylsilyl)Oxy]-, [2As-(2A-α-,3-α-,4Z,7B-α-)]- is a high-purity, complex heterocyclic compound featuring a fused oxa-aza ring system and a trimethylsilyl (TMS) protecting group. This molecule is of significant value as a sophisticated synthetic intermediate, particularly in the development of novel pharmaceuticals and advanced organic materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and anti-infective drug research.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides with complex heterocyclic cores.
• Advanced Material Precursor: Serves as a monomer or precursor in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for methodological studies in stereoselective synthesis and protecting group chemistry.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme inhibition.

Basic Information

Item	Information
Product Name	1H-2-Oxa-7A-Azacyclopent[Cd]Inden-1-One, 4-Ethylidene-2A,3,4,6,7,7B-Hexahydro-3-[(Trimethylsilyl)Oxy]-, [2As-(2A-α-,3-α-,4Z,7B-α-)]-
CAS No.	127599-68-2
Molecular Formula	C15H23NO2Si
Molecular Weight	277.44 g/mol
Synonyms	4-Ethylidene-3-(trimethylsilyloxy)-2a,3,4,6,7,7b-hexahydro-1H-2-oxa-7a-azacyclopent[cd]inden-1-one; (2aS,3S,4Z,7bS)-4-Ethylidene-3-[(trimethylsilyl)oxy]-2a,3,4,6,7,7b-hexahydro-1H-2-oxa-7a-azacyclopent[cd]inden-1-one; TMS-protected oxa-aza indanone derivative; Complex fused heterocycle with TMS ether; Advanced pharmaceutical intermediate 127599-68-2.
EINECS	Contact for details

Quality Control

Our 1H-2-Oxa-7A-Azacyclopent[Cd]Inden-1-One derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed chromatographic data and impurity profiles upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.