Description

Ethyl 2,3,4-Tri-o-Acetyl-1-Thio-β-L-Fucopyranoside is a key thioglycoside building block in synthetic carbohydrate chemistry. This compound is essential for the efficient synthesis of complex oligosaccharides and glycoconjugates, enabling precise control over glycosidic linkage formation. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for developing novel therapeutics, vaccines, and biochemical probes.

Application

• Glycosylation Reagent: A crucial donor molecule in the stereoselective synthesis of L-fucose-containing oligosaccharides and glycans.
• Pharmaceutical Intermediate: Used in the research and development of carbohydrate-based drugs, including anti-inflammatory and anti-cancer agents.
• Glycoconjugate Synthesis: Building block for creating neoglycoconjugates, glycoproteins, and glycolipids for biological studies and diagnostic applications.
• Chemical Biology Probes: Serves as a precursor for labeled fucose derivatives used to study fucosylation pathways and cell-surface interactions.
• Enzyme Substrate/Analog: Potential substrate or inhibitor for fucosyltransferases and other glycosyl-processing enzymes in biochemical assays.
• Material Science: Intermediate for synthesizing specialized carbohydrate-based polymers and surfaces with specific biological recognition properties.

Basic Information

Product Name	Ethyl 2,3,4-Tri-o-Acetyl-1-Thio-β-L-Fucopyranoside
CAS No.	127501-41-1
Molecular Formula	C14H22O8S
Molecular Weight	350.39 g/mol
Synonyms	Ethyl 1-Thio-β-L-fucopyranoside 2,3,4-triacetate; 1-Thioethyl 2,3,4-tri-O-acetyl-β-L-fucopyranoside; Ethyl 2,3,4-Tri-O-acetyl-1-thio-β-L-fucopyranoside; β-L-Fucopyranoside, ethyl 2,3,4-tri-O-acetyl-1-thio-; Ethyl 1-Thio-β-L-fucoside triacetate; ETFA; Thioglycoside donor L-fucose derivative
EINECS	Contact for details

Quality Control

Our Ethyl 2,3,4-Tri-o-Acetyl-1-Thio-β-L-Fucopyranoside is produced under controlled conditions to ensure high chemical purity and batch-to-batch consistency, suitable for demanding synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and optical rotation analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformity to customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.