Description

2,3-Dihydro-6-[[[(5R)-5,6,7,8-Tetrahydro-6-Methyl-1,3-Dioxolo[4,5-G]Isoquinolin]-5β-Yl]Methyl]Benzofuran-7-Carboxylic Acid is a complex, high-purity organic compound of significant interest in advanced pharmaceutical research and development. This molecule serves as a critical advanced pharmaceutical intermediate (API intermediate) or a key scaffold for synthesizing novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex active pharmaceutical ingredients (APIs) targeting specific biological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for designing and optimizing new chemical entities in drug discovery programs.
• Biochemical Research: Employed in studies investigating enzyme inhibition or receptor-ligand interactions due to its specific structural features.
• Process Development: Serves as a reference standard or starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.

Basic Information

Product Name	2,3-Dihydro-6-[[[(5R)-5,6,7,8-Tetrahydro-6-Methyl-1,3-Dioxolo[4,5-G]Isoquinolin]-5β-Yl]Methyl]Benzofuran-7-Carboxylic Acid
CAS No.	127460-61-1
Molecular Formula	C22H23NO5
Molecular Weight	381.42 g/mol
Synonyms	6-[[(5R)-5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]methyl]-2,3-dihydro-1-benzofuran-7-carboxylic acid; (R)-6-((5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)methyl)-2,3-dihydrobenzofuran-7-carboxylic acid; 127460-61-1; UNII-9S5B1V7H2R; 9S5B1V7H2R; Benzofuran-7-carboxylic acid, 2,3-dihydro-6-[[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]methyl]-
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and purity for research applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Quality is verified using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. We support development projects requiring material produced under GMP-like conditions for preclinical and clinical studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.