Description

2-(Mercaptomethyl)-4-Methylpentanoic Acid is a specialized organosulfur compound featuring both a carboxylic acid and a thiol functional group. This unique bifunctional structure makes it a valuable intermediate for synthesizing complex molecules, particularly in the pharmaceutical and fine chemical industries. It is primarily sought after by research and development chemists, process engineers, and manufacturers involved in creating active pharmaceutical ingredients (APIs), peptide mimetics, and advanced material precursors.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially those targeting enzyme inhibition or requiring specific chiral centers.
• Peptidomimetic Synthesis: Used to introduce thioether linkages or modified amino acid residues into peptide chains, enhancing metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for creating chelating ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Employed to incorporate thiol groups into polymer backbones for cross-linking, adhesion promotion, or creating responsive materials.
• Fine Chemical Production: An intermediate in the multi-step synthesis of complex agrochemicals, flavors, and fragrances.
• Bioconjugation Chemistry: Utilized for site-specific labeling or functionalization of proteins and other biomolecules via its reactive thiol group.

Basic Information

Product Name	2-(Mercaptomethyl)-4-Methylpentanoic Acid
CAS No.	127376-66-3
Molecular Formula	C7H14O2S
Molecular Weight	162.25 g/mol
Synonyms	4-Methyl-2-(mercaptomethyl)pentanoic Acid; 2-(Mercaptomethyl)-4-methylvaleric Acid; 4-Methyl-2-(mercaptomethyl)valeric Acid; (RS)-2-(Mercaptomethyl)-4-methylpentanoic Acid; (±)-2-(Mercaptomethyl)-4-methylpentanoic Acid; DL-2-(Mercaptomethyl)-4-methylpentanoic Acid; 127376-66-3; 2-Mercaptomethyl-4-methylpentanoic acid
EINECS	Contact for details

Quality Control

Our production of 2-(Mercaptomethyl)-4-Methylpentanoic Acid adheres to stringent quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency, with analytical methods including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its highly volatile and easily oxidized nature, minimize exposure to air and handle in a fume hood.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.