Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 3-Methyl-, (1S,2S,3R,4R)- (9Ci) is a high-purity, stereochemically defined chiral building block essential for advanced organic synthesis. Its rigid, functionalized norbornene core structure makes it a critical intermediate for constructing complex molecules with precise three-dimensional architecture. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in asymmetric catalysis, medicinal chemistry, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific pesticides and herbicides where the defined spatial orientation of the molecule is crucial for biological activity.
• Asymmetric Catalyst Ligand Precursor: The carboxylic acid functionality and chiral centers provide a platform for developing novel ligands used in enantioselective catalysis.
• Material Science Research: Acts as a monomer or cross-linking agent in the synthesis of specialized polymers with unique thermal or mechanical properties derived from the norbornene framework.
• Fine Chemical Production: Employed in the multistep synthesis of complex fragrance compounds, flavors, and other high-value specialty chemicals.
• Academic & Institutional R&D: A valuable tool for synthetic organic chemists in universities and research institutes studying cycloaddition reactions and stereochemistry.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 3-Methyl-, (1S,2S,3R,4R)- (9Ci)
CAS No.	127179-45-7
Molecular Formula	C9H12O2
Molecular Weight	152.19 g/mol
Synonyms	(1S,2S,3R,4R)-3-Methylbicyclo[2.2.1]hept-5-ene-2-carboxylic acid; endo-(1S,2S,3R,4R)-3-Methyl-5-norbornene-2-carboxylic Acid; 3-Methyl-2-norbornene-2-carboxylic Acid (specific isomer); Chiral Norbornene Carboxylic Acid Derivative; (1S,2S,3R,4R)-3-Methyl-2-norbornene-5-carboxylic Acid
EINECS	Contact for details

Quality Control

Every batch of our chiral intermediates is produced and verified under a strict quality management system. We employ advanced analytical techniques, including chiral HPLC, GC, and NMR, to guarantee exceptional stereochemical purity and chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with each shipment to ensure full traceability and compliance with your research or production protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be sensitive to prolonged exposure to air and moisture; therefore, containers should be kept sealed under an inert atmosphere when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.