Description

Methylamine Hydrochloride, [Methyl-3H] is a tritium-labeled derivative of methylamine hydrochloride, a fundamental building block in organic synthesis. This isotopically labeled compound is essential for advanced research and development, enabling precise metabolic, pharmacokinetic, and environmental fate studies through radiotracer techniques. It is a critical reagent for scientists and process developers in the pharmaceutical, agrochemical, and life science research sectors who require high-specific-activity materials for autoradiography, ADME (Absorption, Distribution, Metabolism, and Excretion) studies, and mechanistic pathway elucidation.

Application

• Pharmaceutical R&D: As a radiolabeled precursor in the synthesis of tritiated drug candidates for metabolism and distribution studies.
• Metabolic Pathway Tracing: Used in biochemical research to track the incorporation and fate of methyl groups in biological systems.
• Agrochemical Development: Employed in environmental science and pesticide research to study degradation pathways and environmental persistence.
• Autoradiography: Serves as a key starting material for creating labeled compounds used in imaging techniques to visualize biological processes.
• Chemical Mechanism Studies: Utilized in organic chemistry to investigate reaction mechanisms and catalytic cycles involving methyl transfer.
• Quality Control & Reference Standard: Can be used as an internal standard in advanced analytical methods like LC-MS for quantitative analysis.

Basic Information

Product Name	Methylamine Hydrochloride, [Methyl-3H]
CAS No.	127117-27-5
Molecular Formula	C3H3ClN • HCl (Note: C3H3 indicates tritium labeling on the methyl group)
Molecular Weight	Contact for details (Varies with specific activity)
Synonyms	Methanamine hydrochloride (³H-methyl); Tritiated Methylamine Hydrochloride; [³H]Methylamine HCl; Methyl-³H-amine hydrochloride; (³H)Methylammonium chloride; Monomethylamine-³HCl; Aminomethane-³HCl; ³H-CH3NH2•HCl
EINECS	Contact for details

Quality Control

Every batch of our tritium-labeled Methylamine Hydrochloride is produced and analyzed under stringent quality systems to ensure radiochemical purity, chemical purity, and specific activity meet the exacting requirements of research applications. Comprehensive analysis is performed using techniques such as HPLC with radiometric detection. A detailed Certificate of Analysis (COA), which includes data on radionuclidic purity, specific activity (Ci/mmol or GBq/mmol), and solvent composition, is provided with each shipment to ensure full traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at or below -20°C. This product is hygroscopic (moisture-sensitive). For long-term storage of solutions, follow appropriate guidelines for handling and storing radioactive materials. Always store in a designated area compliant with local and international regulations for radioactive substances.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR / NMR)	Conforms to structure
Radiochemical Purity (HPLC)	≥ 95%
Chemical Purity (HPLC)	≥ 98%
Specific Activity	Customizable (e.g., 10-80 Ci/mmol)
Solvent (if supplied as solution)	Specified in COA (e.g., Ethanol, Water)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.