Description

Ethyl Isobutyrate-D6 is a deuterated isotopologue of ethyl isobutyrate, where six hydrogen atoms are replaced by deuterium, making it a valuable stable isotope-labeled compound. This high-purity standard is essential for applications requiring precise internal standards in quantitative mass spectrometry, eliminating interference from endogenous compounds. It is primarily needed by analytical laboratories and research institutions in the pharmaceutical, agrochemical, and flavor/fragrance industries for method development, metabolic studies, and quality control.

Application

• Internal Standard for GC/MS and LC-MS: Used as a quantitative reference standard in mass spectrometric analysis of its non-deuterated counterpart and related esters.
• Metabolic Pathway Tracing: Employed in pharmacokinetic and drug metabolism studies to track the fate of compounds using stable isotope labeling.
• Flavor and Fragrance Research: Serves as a labeled analog in the analysis of volatile esters, aiding in authenticity testing and component quantification.
• NMR Spectroscopy Solvent & Reagent: Utilized as a deuterated solvent or reagent in nuclear magnetic resonance spectroscopy to avoid proton interference.
• Chemical Synthesis Intermediate: Acts as a building block for the synthesis of more complex deuterated molecules for research purposes.
• Environmental Analysis: Applied as a standard in trace analysis of volatile organic compounds (VOCs) in environmental samples.

Basic Information

Product Name	Ethyl Isobutyrate-D6
CAS No.	127074-27-5
Molecular Formula	C6D6H4O2 or C2D5OC(O)CD(CD3)2
Molecular Weight	120.18 g/mol
Synonyms	Ethyl 2-methylpropanoate-d6; Ethyl 2-methylpropionate-d6; Deuterated Ethyl Isobutyrate; Ethyl Isobutyrate (hexadeuterated); Isobutyric Acid Ethyl Ester-d6; Ethyl Isobutanoate-d6; 2-Methylpropanoic Acid Ethyl Ester-d6; [2H6]-Ethyl Isobutyrate
EINECS	Contact for details

Quality Control

Our Ethyl Isobutyrate-D6 is produced under strict quality management protocols to ensure the highest isotopic and chemical purity required for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (Atom % D), chemical purity by GC, and identity confirmation. We support compliance with relevant GLP and ISO 17025 standards for research and analytical use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept upright and sealed when not in use to prevent evaporation and potential concentration changes.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR/NMR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Purity (Atom % D)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.