Description

Methyl 5-Chloro-3-Chlorosulfonyl-Thiophene-2-Carboxylate is a high-purity, multi-functional chemical intermediate essential for advanced organic synthesis. Its unique thiophene core, activated by chloro and chlorosulfonyl groups, makes it a critical building block for creating complex molecules with specific electronic and structural properties. This compound is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the thiophene scaffold for enhanced bioactivity.
• Material Science Research: Serves as a monomer or building block for creating conductive polymers, organic semiconductors, and advanced functional materials.
• Dye and Pigment Manufacturing: Intermediate for producing specialized heterocyclic dyes and pigments with improved lightfastness and color properties.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic and Industrial R&D: Utilized in research laboratories for method development and exploring new chemical reactions involving sulfonyl chlorides and ester functionalities.

Basic Information

Product Name	Methyl 5-Chloro-3-Chlorosulfonyl-Thiophene-2-Carboxylate
CAS No.	126910-68-7
Molecular Formula	C7H4Cl2O4S2
Molecular Weight	279.14 g/mol
Synonyms	5-Chloro-3-(chlorosulfonyl)thiophene-2-carboxylic acid methyl ester; Methyl 5-chloro-3-(chlorosulfonyl)-2-thiophenecarboxylate; 2-Thiophenecarboxylic acid, 5-chloro-3-(chlorosulfonyl)-, methyl ester; 3-Chlorosulfonyl-5-chlorothiophene-2-carboxylic acid methyl ester; 5-Chloro-3-chlorosulfonylthiophene-2-carboxylic acid methyl ester; Methyl 5-chloro-3-chlorosulfonylthiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl 5-Chloro-3-Chlorosulfonyl-Thiophene-2-Carboxylate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and moisture content. We provide detailed Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your internal specifications and Good Manufacturing Practice (GMP) principles where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.