Description

1,2-Dimethoxybenzene-3,4,5,6-D4 is a deuterated derivative of veratrole, where four hydrogen atoms are replaced by deuterium, a stable isotope of hydrogen. This isotopic labeling is critical for applications requiring precise molecular tracking and reduced metabolic interference in spectroscopic studies. It serves as an essential building block and analytical standard for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in drug discovery and metabolic pathway analysis. The compound is supplied to meet the stringent requirements of advanced research and development.

Application

• Deuterated Internal Standard for quantitative analysis via GC-MS or LC-MS in pharmacokinetic and metabolomic studies.
• Precursor for Labeled Compounds in the synthesis of deuterated active pharmaceutical ingredients (APIs) and agrochemicals for metabolic stability testing.
• NMR Solvent & Reagent used in nuclear magnetic resonance spectroscopy to study molecular structures and dynamics without proton signal interference.
• Mechanistic Probe in chemical reaction studies to investigate kinetic isotope effects (KIE) and reaction pathways.
• Pharmaceutical Research for developing deuterated drugs, where the deuterium substitution can improve metabolic stability and pharmacokinetic profiles.
• Material Science Research as a labeled monomer or additive in polymer studies to trace material properties and degradation.

Basic Information

Product Name	1,2-Dimethoxybenzene-3,4,5,6-D4
CAS No.	126840-15-1
Molecular Formula	C8H4D4O2
Molecular Weight	156.20 g/mol
Synonyms	Veratrole-d4; 1,2-Dimethoxybenzene-d4; o-Dimethoxybenzene-d4; Deuterated Veratrole; [2H4]-1,2-Dimethoxybenzene; 3,4,5,6-Tetradeutero-1,2-dimethoxybenzene; Benzene-d4, 1,2-dimethoxy-
EINECS	Contact for details

Quality Control

Our 1,2-Dimethoxybenzene-3,4,5,6-D4 is produced under controlled conditions to ensure high isotopic and chemical purity, meeting the exacting standards for research and industrial use. Each batch undergoes rigorous analytical testing, including NMR, GC-MS, and HPLC, to verify deuterium incorporation, chemical purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing isotopic enrichment (typically >98 atom % D) and full specifications are provided with every shipment to ensure traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Purity (NMR)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.