Description

4-Methoxyphenol-2,3,5,6-D4,Od is a deuterium-labeled isotopologue of 4-methoxyphenol, a compound of significant interest in advanced chemical research and development. This stable isotope-labeled material is essential for creating internal standards in mass spectrometry, enabling precise quantitative analysis and metabolic pathway tracing. It is primarily utilized by analytical laboratories, pharmaceutical R&D teams, and agrochemical scientists for applications requiring high isotopic purity and reliable performance.

Application

• Internal Standard for LC-MS/MS: Used as a quantitative reference standard in liquid chromatography-tandem mass spectrometry for accurate measurement of 4-methoxyphenol and related compounds in complex matrices.
• Metabolic Pathway Studies: Employed in pharmaceutical and biochemical research to trace the metabolic fate and degradation pathways of phenolic compounds.
• Deuterated Reference Material: Serves as a critical reference material in NMR spectroscopy and other analytical techniques where isotopic labeling is required to avoid signal interference.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of impurities and degradants in drug substances and products.
• Environmental Analysis: Facilitates the sensitive detection and monitoring of phenolic antioxidants or their breakdown products in environmental samples.
• Chemical Mechanism Elucidation: Used in mechanistic studies to understand reaction pathways and kinetics in organic synthesis and catalysis.

Basic Information

Product Name	4-Methoxyphenol-2,3,5,6-D4,Od
CAS No.	126840-02-6
Molecular Formula	C7H4D4O2
Molecular Weight	128.16 g/mol (approx.)
Synonyms	4-Methoxyphenol-d4; p-Methoxyphenol-d4; Hydroquinone Monomethyl Ether-d4; Mequinol-d4; 1-Hydroxy-4-methoxybenzene-d4; 4-Hydroxyanisole-d4; p-Hydroxyanisole-d4; 4-Methoxyphenol (2,3,5,6-D4)
EINECS	Contact for details

Quality Control

Every batch of 4-Methoxyphenol-2,3,5,6-D4,Od is subjected to rigorous analytical testing to ensure it meets the high standards required for isotopic and chemical purity. Our quality protocols include verification of isotopic enrichment by NMR and mass spectrometry, alongside standard purity assays. A comprehensive Certificate of Analysis (COA) detailing batch-specific results for isotopic purity, chemical purity, and identity is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, prolonged exposure to air should be avoided. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Isotopic Purity (D-content)	≥ 98 atom % D (by 1H NMR/MS)
Chemical Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.