Description

iso-Propyl-1,1,1,3,3,3-D6-Amine Hcl is a deuterated isotopologue of isopropylamine hydrochloride, where six hydrogen atoms are replaced by deuterium, a stable hydrogen isotope. This deuteration is critical for applications requiring reduced metabolic interference or enhanced analytical sensitivity, such as in mass spectrometry and NMR spectroscopy. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors for use as an internal standard, a labeled precursor in synthesis, or a probe in mechanistic studies.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference standard in LC-MS and GC-MS analyses due to its isotopic purity and predictable mass shift.
• Deuterated Precursor in Synthesis: Serves as a building block for the synthesis of deuterium-labeled pharmaceutical compounds and agrochemicals for metabolic and pharmacokinetic studies.
• NMR Spectroscopy Solvent/Reagent: Employed as a probe or shift reagent in nuclear magnetic resonance spectroscopy to study molecular structure and dynamics.
• Metabolic Research: Facilitates the tracing of metabolic pathways and the study of drug metabolism without interference from the protiated form.
• Chemical Reaction Mechanism Studies: Acts as a tool in kinetic isotope effect (KIE) studies to elucidate reaction mechanisms in organic and organometallic chemistry.
• Quality Control & Method Development: Used in analytical laboratories for developing and validating sensitive detection methods for amines and related compounds.

Basic Information

Product Name	iso-Propyl-1,1,1,3,3,3-D6-Amine Hcl
CAS No.	126794-59-0
Molecular Formula	C3D6ClN • HCl
Molecular Weight	117.62 g/mol (for C3D6ClN • HCl)
Synonyms	Deuterated Isopropylamine Hydrochloride; (1,1,1,3,3,3-Hexadeutero-2-propyl)amine hydrochloride; 2-Propanamine-1,1,1,3,3,3-d6 hydrochloride; Isopropylamine-d6 hydrochloride; (CD3)2CDNH2 • HCl; Perdeuterated isopropylamine HCl; D6-Isopropylamine HCl; 2-Aminopropane-d6 hydrochloride
EINECS	Contact for details

Quality Control

Our deuterated chemicals are produced and tested under stringent conditions to ensure high isotopic and chemical purity. Each batch of iso-Propyl-1,1,1,3,3,3-D6-Amine Hcl is accompanied by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic purity (D-atom %), chemical purity (by NMR/HPLC), and impurity profiles. We adhere to relevant quality guidelines for research chemicals. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccator for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC/NMR)	≥ 98% (Chemical Purity)
Isotopic Purity (D-atom %)	≥ 98% (by MS or NMR)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.