Description

Ethyl 1-(Cyanomethyl)-1H-Indole-2-Carboxylate is a versatile indole-based building block and key synthetic intermediate of significant importance in advanced organic synthesis. Its molecular architecture, featuring both an ester and a cyanomethyl group on the indole nitrogen, makes it a critical precursor for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and pharmaceutical development companies engaged in the creation of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of complex indole alkaloids and potential drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators that leverage the indole scaffold.
• Material Science: Serves as a monomer or precursor for specialty polymers and advanced organic materials with specific electronic or photophysical properties.
• Academic & R&D: Employed in methodological chemistry research for developing new synthetic routes and studying heterocyclic chemistry.
• Dye & Pigment Intermediate: Acts as a precursor for synthesizing specialized indole-based dyes and functional colorants.

Basic Information

Product Name	Ethyl 1-(Cyanomethyl)-1H-Indole-2-Carboxylate
CAS No.	126718-04-5
Molecular Formula	C13H12N2O2
Molecular Weight	228.25 g/mol
Synonyms	1H-Indole-2-carboxylic acid, 1-(cyanomethyl)-, ethyl ester; Ethyl 1-cyanomethylindole-2-carboxylate; 1-(Cyanomethyl)-1H-indole-2-carboxylic acid ethyl ester; 2-Carbethoxy-1-cyanomethylindole; NSC 405122; Ethyl 1-(cyanomethyl)indole-2-carboxylate; 1-Cyanomethyl-1H-indole-2-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 1-(Cyanomethyl)-1H-Indole-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.