Description

1-Piperazin-1-Yl-Isoquinoline is a versatile heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmacologically active molecules, particularly in medicinal chemistry research. Pharmaceutical R&D laboratories and fine chemical manufacturers need it for constructing complex molecular architectures targeting various therapeutic areas.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and high-throughput screening libraries.
• Ligand Synthesis: Used in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Agrochemical Development: Employed as a building block for creating new active ingredients in crop protection research.
• Dye and Pigment Chemistry: Acts as an intermediate in the synthesis of specialized heterocyclic dyes and functional materials.
• Academic & Industrial R&D: Fundamental research tool in organic synthesis for exploring new heterocyclic reactions and methodologies.

Basic Information

Product Name	1-Piperazin-1-Yl-Isoquinoline
CAS No.	126653-00-7
Molecular Formula	C₁₃H₁₅N₃
Molecular Weight	213.28 g/mol
Synonyms	1-(Isoquinolin-1-yl)piperazine; 1-(1-Piperazinyl)isoquinoline; Isoquinolin-1-yl-piperazine; 1-Piperazinylisoquinoline; 1-(Piperazin-1-yl)isoquinoline; 1-Isoquinolinylpiperazine; UNII-9Q2W8Q3F1I; 9Q2W8Q3F1I
EINECS	Contact for details

Quality Control

Our 1-Piperazin-1-Yl-Isoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and development applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.