Description

1,2:5,6-Di-o-Isopropylidene-α-D-Glucofuranose-1,2,3,4,5,6-13C6 is a high-purity, uniformly carbon-13 labeled derivative of D-glucose, serving as a critical stable isotope-labeled intermediate. This compound is essential for advanced research and development where precise metabolic tracing and structural elucidation are required. It is primarily utilized by pharmaceutical researchers, analytical laboratories, and academic institutions working on carbohydrate chemistry, metabolic pathway studies, and the synthesis of labeled bioactive molecules.

Application

• Stable Isotope Labeling: Acts as a key precursor for the synthesis of carbon-13 labeled sugars, nucleotides, and glycoconjugates for metabolic flux analysis and tracer studies.
• Pharmaceutical Research: Used in the development and validation of analytical methods (e.g., LC-MS, NMR) for drug metabolism and pharmacokinetics (DMPK) studies involving carbohydrate-based therapeutics.
• Biochemical Probes: Serves as a building block for creating isotopically labeled probes to investigate enzymatic mechanisms and carbohydrate-processing pathways.
• NMR Spectroscopy: Provides an internal standard or a well-defined labeled compound for nuclear magnetic resonance spectroscopy, enhancing signal detection and structural analysis.
• Academic & Industrial R&D: Fundamental research tool in synthetic organic chemistry for constructing complex, labeled molecular architectures.

Basic Information

Item	Details
Product Name	1,2:5,6-Di-o-Isopropylidene-α-D-Glucofuranose-1,2,3,4,5,6-13C6
CAS No.	126590-65-6
Molecular Formula	C12H1813C6O6
Molecular Weight	~288.23 (based on 13C6 labeling)
Synonyms	1,2:5,6-Di-O-Isopropylidene-α-D-glucofuranose-13C6; D-Glucose-13C6 1,2:5,6-Diisopropylidene Acetal; 1,2:5,6-Di-O-(1-methylethylidene)-α-D-glucofuranose-13C6; Diacetone Glucose-13C6; Diacetone-D-glucose-13C6; (3aR,5R,6S,6aR)-5-((R)-1,2-Dihydroxyethyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole-6-ol-13C6
EINECS	Contact for details

Quality Control

Our 1,2:5,6-Di-o-Isopropylidene-α-D-Glucofuranose-1,2,3,4,5,6-13C6 is manufactured under strict quality control protocols to ensure high isotopic and chemical purity suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and identity confirmation. We adhere to industry-standard analytical practices, and specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (13C)	≥ 99 atom % 13C
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.