Description

2-Methoxyphenylphosphine is a versatile organophosphorus compound featuring a methoxy-substituted phenyl ring directly bonded to a phosphine group. This structure makes it a valuable specialty ligand and building block in advanced chemical synthesis, particularly for catalysis and materials science. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing novel compounds and catalytic processes.

Application

• Catalyst Ligand in Cross-Coupling Reactions: Serves as a key ligand for transition metal catalysts (e.g., palladium, nickel) in Suzuki, Heck, and Buchwald-Hartwig amination reactions.
• Pharmaceutical Intermediate: Used in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs) requiring specific phosphine-based motifs.
• Agrochemical Synthesis: Acts as a precursor or intermediate in the production of specialized pesticides and herbicides.
• Material Science Precursor: Employed in the development of novel polymers, ligands for metal-organic frameworks (MOFs), and other functional materials.
• Organic Synthesis Reagent: Functions as a nucleophilic phosphine reagent in various organic transformations, including reductions and Wittig-type reactions.
• Research & Development: A critical tool in academic and industrial R&D for exploring new catalytic systems and synthetic methodologies.

Basic Information

Product Name	2-Methoxyphenylphosphine
CAS No.	126590-38-3
Molecular Formula	C7H9OP
Molecular Weight	140.12 g/mol
Synonyms	(2-Methoxyphenyl)phosphine; o-Methoxyphenylphosphine; 2-Methoxybenzenephosphine; Phosphinous acid, O-methyl ester (tautomer); P-(2-Methoxyphenyl)phosphine
EINECS	Contact for details

Quality Control

Our 2-Methoxyphenylphosphine is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including NMR, GC/HPLC, and titration methods, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality systems support development from laboratory to commercial scale.

Storage

Preserve in a tightly closed container, protected from light. Due to its easily oxidized nature, this product must be stored under an inert atmosphere (argon or nitrogen). Recommended storage temperature is 2-8°C. Keep the container in a cool, dry, well-ventilated place, away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.