Description

Ethyl 2,3,4-Tri-o-Benzyl-1-Thio-B-D-Glucopyranoside is a protected thioglycoside derivative of glucose, serving as a crucial synthetic intermediate in carbohydrate and medicinal chemistry. This compound matters for its role as a versatile glycosyl donor, enabling the stereoselective construction of complex oligosaccharides and glycoconjugates under mild conditions. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of glycosidase inhibitors, antiviral agents, and novel carbohydrate-based therapeutics.

Application

• Glycosylation Reagent: A key building block for the stereoselective synthesis of O-glycosides, S-glycosides, and C-glycosides.
• Oligosaccharide Synthesis: Used in the iterative construction of complex oligosaccharide chains for biological studies and drug discovery.
• Glycoconjugate Preparation: Essential for creating glycopeptides, glycolipids, and other biologically active glycoconjugates.
• Medicinal Chemistry Intermediate: Serves as a precursor in the synthesis of glycosidase inhibitors and potential antiviral or anticancer agents.
• Chemical Biology Probes: Utilized to develop activity-based probes for studying glycosidase enzymes and carbohydrate-processing pathways.
• Process Development: Employed in scale-up and process optimization for the manufacture of carbohydrate-based active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Ethyl 2,3,4-Tri-o-Benzyl-1-Thio-B-D-Glucopyranoside
CAS No.	126461-54-9
Molecular Formula	C29H34O5S
Molecular Weight	494.64 g/mol
Synonyms	Ethyl 2,3,4-Tri-O-benzyl-1-thio-β-D-glucopyranoside; 1-Thioethyl 2,3,4-tri-O-benzyl-β-D-glucopyranoside; Ethyl 2,3,4-Tri-O-benzyl-1-thio-β-D-glucoside; β-D-Glucopyranoside, ethyl 2,3,4-tri-O-benzyl-1-thio-; ETBG; Tri-O-benzyl protected ethyl thioglucoside; Ethyl 1-thio-2,3,4-tri-O-benzyl-β-D-glucopyranoside
EINECS	Contact for details

Quality Control

Our Ethyl 2,3,4-Tri-o-Benzyl-1-Thio-B-D-Glucopyranoside is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure compliance with research and development standards. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee reproducible performance in sensitive synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). For long-term storage, consider storing under an inert gas such as argon or nitrogen in a sealed container.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure (1H & 13C)
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.