Description

8,9-Di-o-Methyl-Urolithin C is a specific methylated derivative of the urolithin class of compounds, which are gut-microbiota metabolites of ellagitannins and ellagic acid. This compound is valued for its role as a key reference standard and research-grade biochemical in the study of polyphenol metabolism and bioactivity. It is primarily required by pharmaceutical R&D laboratories, nutraceutical ingredient developers, and academic research institutions focused on metabolic pathways, aging, and inflammation.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis (HPLC, LC-MS) of urolithin metabolites in drug development and pharmacokinetic studies.
• Nutraceutical Research: Serves as a critical biomarker and active ingredient prototype in the development of advanced dietary supplements targeting cellular health and mitophagy.
• Biochemical Pathway Investigation: Employed in in vitro and in vivo studies to elucidate the biological effects of ellagitannin-derived metabolites on inflammation and oxidative stress.
• Analytical Method Development: Essential for calibrating instruments and validating analytical methods in contract research organizations (CROs) and quality control labs.
• Preclinical Studies: Utilized in animal model research to investigate the bioavailability, metabolism, and efficacy of polyphenol-based interventions.

Basic Information

Item	Detail
Product Name	8,9-Di-o-Methyl-Urolithin C
CAS No.	126438-35-5
Molecular Formula	C17H14O6
Molecular Weight	314.29 g/mol
Synonyms	8,9-Di-O-methylurolithin C; 3,8,9-Trihydroxy-6H-dibenzo[b,d]pyran-6-one, 8,9-dimethoxy-; Urolithin C 8,9-dimethyl ether; 8,9-Dimethoxy-urolithin C; 6H-Dibenzo[b,d]pyran-6-one, 3,8,9-trihydroxy-8,9-dimethoxy-; 8,9-Dimethoxy-3,8,9-trihydroxy-6H-dibenzo[b,d]pyran-6-one
EINECS	Contact for details

Quality Control

Our 8,9-Di-o-Methyl-Urolithin C is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for research chemicals, and custom synthesis and purification to meet specific project requirements are available.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere for long-term preservation. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.