Description

7-Amino-3-(2-bromoethoxy)-4-chloroisocoumarin is a specialized heterocyclic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring reactive amino, bromoethoxy, and chloro substituents on the isocoumarin core, makes it a versatile precursor for constructing complex pharmacophores. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly those targeting protease enzymes, due to the reactive isocoumarin scaffold.
• Agrochemical Research: Serves as a building block in the development of new herbicides, fungicides, or insecticides with potential novel modes of action.
• Chemical Biology Probe Development: Used to create activity-based probes (ABPs) for studying enzyme function and inhibition in biological systems.
• Organic Synthesis: Employed in heterocyclic and medicinal chemistry for constructing complex molecular libraries via further functionalization of its amino and halogenated alkoxy groups.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials or advanced polymers with specific photophysical properties.

Basic Information

Product Name	7-Amino-3-(2-bromoethoxy)-4-chloroisocoumarin
CAS No.	126062-22-4
Molecular Formula	C11H9BrClNO3
Molecular Weight	318.55 g/mol
Synonyms	4-Chloro-7-amino-3-(2-bromoethoxy)isocoumarin; 3-(2-Bromoethoxy)-4-chloro-7-aminoisocoumarin; 7-Amino-4-chloro-3-(2-bromoethoxy)-2H-1-benzopyran-2-one; 126062-22-4; 4-Chloro-7-amino-3-(β-bromoethoxy)coumarin; 7-Amino-4-chloro-3-(2-bromoethoxy)coumarin; Isocoumarin, 7-amino-3-(2-bromoethoxy)-4-chloro-
EINECS	Contact for details

Quality Control

Our 7-Amino-3-(2-bromoethoxy)-4-chloroisocoumarin is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant ISO guidelines, and our quality systems are designed to support cGMP-compliant production for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.