Description

1-(2-Aminoethyl)-1H-Pyrrole-2,5-Dione is a versatile heterocyclic building block featuring both an aminoethyl side chain and a maleimide-like pyrrole-2,5-dione core. This unique bifunctional structure makes it a critical intermediate for synthesizing advanced pharmaceutical compounds, specialty polymers, and functional materials. It is particularly valuable for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to incorporate reactive handles for conjugation or polymerization.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for targeted therapies and drug-linker conjugates.
• Bioconjugation Reagent: Used to functionalize proteins, antibodies, or peptides via the reactive maleimide group for antibody-drug conjugates (ADCs) and diagnostic probes.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for creating specialty polymers with tailored thermal or mechanical properties.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, or plant growth regulators.
• Material Science: Used in the development of advanced coatings, adhesives, and functional surfaces.
• Research & Development: Essential compound for academic and industrial R&D in organic synthesis and medicinal chemistry.

Basic Information

Product Name	1-(2-Aminoethyl)-1H-Pyrrole-2,5-Dione
CAS No.	125923-10-6
Molecular Formula	C6H8N2O2
Molecular Weight	140.14 g/mol
Synonyms	N-(2-Aminoethyl)maleimide; 2,5-Pyrroledione, 1-(2-aminoethyl)-; 1-(2-Aminoethyl)-2,5-dihydro-1H-pyrrole-2,5-dione; Maleimide, N-(2-aminoethyl)-; Aminoethylmaleimide; AEM; N-Aminoethylmaleimide
EINECS	Contact for details

Quality Control

Our production of 1-(2-Aminoethyl)-1H-Pyrrole-2,5-Dione adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.