Description

Phenyl-D5-Hydrazine Hydrochloride is a deuterium-labeled derivative of phenylhydrazine hydrochloride, a crucial building block in synthetic organic chemistry. This stable isotope-labeled compound is essential for creating internal standards and labeled analogs used in advanced analytical techniques, ensuring precise and reliable quantitative measurements. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors for applications requiring high isotopic purity and traceability.

Application

• Deuterated Internal Standards: Serves as a critical precursor for synthesizing deuterium-labeled internal standards used in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for accurate quantification of pharmaceuticals and metabolites.
• Pharmaceutical Research & Development: Employed in the synthesis of deuterated drug candidates for pharmacokinetic, metabolic stability (DMPK), and tracer studies, leveraging the kinetic isotope effect.
• Agrochemical Analysis: Used to develop labeled standards for the environmental monitoring and residue analysis of pesticides and herbicides, enhancing detection accuracy.
• Metabolomics and Biomarker Discovery: Facilitates the preparation of isotopically labeled probes for tracking metabolic pathways and identifying biomarkers in complex biological samples.
• Organic Synthesis Intermediate: Acts as a specialized reagent in the synthesis of heterocyclic compounds, dyes, and other fine chemicals where deuterium labeling is required.
• NMR Spectroscopy: Useful as a starting material for preparing deuterated compounds for nuclear magnetic resonance (NMR) studies, aiding in structural elucidation.

Basic Information

Product Name	Phenyl-D5-Hydrazine Hydrochloride
CAS No.	125687-18-5
Molecular Formula	C6D5N2·HCl
Molecular Weight	147.62 g/mol
Synonyms	Pentadeuterophenylhydrazine Hydrochloride; (2,3,4,5,6-Pentadeuterophenyl)hydrazine Hydrochloride; Phenyl-d5 Hydrazine HCl; Hydrazine, (2,3,4,5,6-pentadeuteriophenyl)-, hydrochloride; Phenylhydrazine-d5 Hydrochloride; Deuterated Phenylhydrazine HCl; C6D5NHNH2·HCl
EINECS	Contact for details

Quality Control

Our Phenyl-D5-Hydrazine Hydrochloride is produced under strict quality management protocols to ensure high isotopic and chemical purity, critical for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic purity (D-enrichment), chemical purity (HPLC), and identity confirmation. We adhere to relevant industry standards for stable isotope-labeled compounds, and custom purity grades are available to meet specific research or GMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Isotopic Purity (D-enrichment)	≥98 atom % D
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.