Description

Iralukast is a selective leukotriene receptor antagonist (LTRA) with the CAS registry number 125617-94-9. This compound is a key pharmaceutical intermediate and research chemical, valued for its role in modulating inflammatory pathways. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers engaged in the development of respiratory and anti-inflammatory therapeutics.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced leukotriene receptor antagonist drugs.
• Biochemical Research: Used as a reference standard and active agent in preclinical studies targeting asthma, allergic rhinitis, and other inflammatory conditions.
• Mechanism of Action Studies: Employed in pharmacological research to investigate the cysteinyl leukotriene (CysLT) pathway and receptor binding.
• Fine Chemical Synthesis: Serves as a precursor for the preparation of more complex, targeted therapeutic molecules.
• Reference Material: Supplied as a high-purity standard for analytical method development and quality control in pharmaceutical laboratories.

Basic Information

Product Name	Iralukast
CAS No.	125617-94-9
Molecular Formula	C31H33N3O6S
Molecular Weight	575.68 g/mol
Synonyms	IRALUKAST; Iralukastum; 125617-94-9; 4-[4-[4-[1-(4-Hydroxyphenyl)-1-methylethyl]phenoxy]butyl]thio]-3-methylbenzoic acid; 3-Methyl-4-[[4-[4-[1-(4-hydroxyphenyl)-1-methylethyl]phenoxy]butyl]thio]benzoic acid; Benzoic acid, 3-methyl-4-[[4-[4-[1-(4-hydroxyphenyl)-1-methylethyl]phenoxy]butyl]thio]-; RG 12525; RG-12525
EINECS	Contact for details

Quality Control

Our Iralukast is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets high-grade specifications suitable for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.