Description

5-(2-Naphthalenylsulfonyl)-2,4-Thiazolidinedione is a high-purity, specialized organic compound with a sulfonyl-thiazolidinedione core structure. This compound is valued as a critical pharmaceutical intermediate and research chemical for the development of novel therapeutic agents. It is primarily required by R&D laboratories and manufacturers in the pharmaceutical and biotechnology sectors for synthesis and screening programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting metabolic disorders.
• PPARγ Agonist Research: Serves as a core scaffold for developing and studying peroxisome proliferator-activated receptor gamma (PPARγ) modulators.
• Antidiabetic Agent Development: Used in research for novel thiazolidinedione-based compounds with potential insulin-sensitizing properties.
• Chemical Biology Probes: Employed in academic and industrial research to investigate biological pathways and protein interactions.
• Process Chemistry: Utilized in scale-up and optimization studies for the production of active pharmaceutical ingredients (APIs).
• Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Item	Detail
Product Name	5-(2-Naphthalenylsulfonyl)-2,4-Thiazolidinedione
CAS No.	125518-46-9
Molecular Formula	C₁₃H₉NO₄S₂
Molecular Weight	307.34 g/mol
Synonyms	5-(Naphthalen-2-ylsulfonyl)-1,3-thiazolidine-2,4-dione; 2,4-Thiazolidinedione, 5-[(2-naphthalenyl)sulfonyl]-; 5-(2-Naphthylsulfonyl)thiazolidine-2,4-dione; 5-(2-Naphthalenesulfonyl)-2,4-thiazolidinedione; TZD sulfonamide derivative; Naphthalene-2-sulfonyl-thiazolidinedione; PPARγ ligand intermediate
EINECS	Contact for details

Quality Control

Every batch of 5-(2-Naphthalenylsulfonyl)-2,4-Thiazolidinedione is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements for pharmaceutical intermediates and research chemicals. A comprehensive Certificate of Analysis (COA) detailing purity by HPLC, identity confirmation (IR, NMR), and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.