Description

2-(Trimethylsilyl)Ethanesulfonamide, 90% is a versatile organosilicon reagent featuring a sulfonamide functional group protected by a trimethylsilyl moiety. This compound is valued for its role as a key synthetic intermediate and protecting group in advanced organic synthesis, particularly for sensitive molecules. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, especially those requiring sulfonamide or sulfonyl chloride functionalities.
• Protecting Group Reagent: Used to temporarily protect sulfonamide groups during multi-step synthetic sequences, allowing for selective reactions at other sites on the molecule.
• Agrochemical Synthesis: Employed in the research and development of new herbicides, fungicides, and insecticides where the sulfonamide group is a key pharmacophore.
• Material Science Research: Acts as a precursor or modifying agent in the creation of specialty polymers and advanced materials with tailored surface properties.
• Process Chemistry: Utilized in scale-up and optimization of manufacturing routes for high-value fine chemicals.
• Cross-Coupling Reactions: Can function as a substrate or reagent in palladium-catalyzed and other metal-mediated coupling reactions to form carbon-sulfur or carbon-nitrogen bonds.

Basic Information

Product Name	2-(Trimethylsilyl)Ethanesulfonamide, 90%
CAS No.	125486-96-6
Molecular Formula	C5H15NO2SSi
Molecular Weight	181.34 g/mol
Synonyms	2-(Trimethylsilyl)ethanesulfonamide; N-Trimethylsilylethanesulfonamide; TES-NH2; 2-(Trimethylsilyl)ethanesulfonic acid amide; (2-Sulfamoylethyl)trimethylsilane; Trimethyl(2-sulfamoylethyl)silane; 2-Trimethylsilylethanesulfonamide; N-(2-Trimethylsilylethyl)sulfonamide
EINECS	Contact for details

Quality Control

Our 2-(Trimethylsilyl)Ethanesulfonamide, 90% is produced under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and physical characteristics is provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 90.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.