Description

5-Chloro-4-Methylthiazole is a versatile and high-purity heterocyclic building block essential for advanced organic synthesis. This compound is valued for its unique thiazole core, which serves as a critical scaffold in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole moiety.
• Material Science Research: Serves as a building block for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a reactive handle or linker in the design of chemical probes and bioconjugates for studying biological systems.
• Dye & Pigment Manufacturing: Acts as an intermediate in the production of specialized dyes and optical brighteners.
• Flavor & Fragrance Industry: Utilized in the synthesis of certain sulfur-containing aroma compounds, contributing to complex flavor profiles.

Basic Information

Item	Detail
Product Name	5-Chloro-4-Methylthiazole
CAS No.	125402-79-1
Molecular Formula	C4H4ClNS
Molecular Weight	133.60 g/mol
Synonyms	4-Methyl-5-chlorothiazole; 5-Chloro-4-methyl-1,3-thiazole; 5-Chloro-4-methyl-thiazole; Thiazole, 5-chloro-4-methyl-; 4-Methyl-5-chloro-thiazole
EINECS	Contact for details

Quality Control

Our 5-Chloro-4-Methylthiazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. We provide Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. The container should be kept tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.