Description

4-Benzyloxy-1-Chlorobutane is a versatile bifunctional organic intermediate featuring both a benzyl-protected alcohol and a reactive alkyl chloride moiety. This compound is valued for its role as a key building block in the synthesis of more complex molecules, particularly in pharmaceutical and fine chemical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing molecular scaffolds and introducing functional groups.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a butyl ether linkage or a chlorobutyl side chain.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and plant growth regulators where its structure serves as a versatile linker.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands for metal catalysis and organocatalysts.
• Polymer Chemistry: Acts as a monomer or chain modifier in the production of specialty polymers and resins.
• Organic Synthesis Building Block: Employed in nucleophilic substitution reactions to introduce the 4-benzyloxybutyl group into target molecules.
• Protecting Group Chemistry: The benzyloxy group can be used for temporary protection of hydroxyl functions during multi-step syntheses.

Basic Information

Product Name	4-Benzyloxy-1-Chlorobutane
CAS No.	125340-68-3
Molecular Formula	C11H15ClO
Molecular Weight	198.69 g/mol
Synonyms	1-Chloro-4-(benzyloxy)butane; 4-(Benzyloxy)butyl chloride; (4-Chlorobutoxy)methylbenzene; Butane, 1-chloro-4-(phenylmethoxy)-; Benzyl 4-chlorobutyl ether; 4-Benzyloxybutyl chloride; NSC 403120
EINECS	Contact for details

Quality Control

Our 4-Benzyloxy-1-Chlorobutane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including assay by GC/HPLC, identity confirmation (IR, NMR), and impurity profiling to ensure high chemical purity and lot-to-lot consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids, bases, and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability, though the product is stable at controlled room temperature (15-25°C) for shorter periods. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%
Refractive Index (n20D)	1.5080 - 1.5120
Density (g/mL at 20°C)	1.050 - 1.090

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.