Description

(E)-n-(2-Oxoindolin-3-Ylidene)-2-(p-Tolyloxy)Acetohydrazide is a specialized organic compound belonging to the class of indolinone-based hydrazide derivatives. This high-purity chemical intermediate is valued for its unique molecular structure, which serves as a critical building block in advanced synthetic chemistry. It is primarily sought by research institutions and pharmaceutical development companies engaged in the synthesis of novel bioactive molecules and heterocyclic compounds for therapeutic applications.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of new drug candidates, particularly those targeting kinase inhibition or other enzyme-related pathways.
• Organic Synthesis Building Block: Used in the construction of complex heterocyclic frameworks and for introducing specific functional groups in multi-step synthetic routes.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore and optimize biological activity profiles of lead compounds.
• Chemical Reference Standard: Serves as an analytical standard for quality control and method development in laboratories characterizing similar molecular entities.
• Agrochemical Research: Investigated as a potential intermediate in the synthesis of novel crop protection agents and pesticides.

Basic Information

Product Name	(E)-n-(2-Oxoindolin-3-Ylidene)-2-(p-Tolyloxy)Acetohydrazide
CAS No.	125299-00-5
Molecular Formula	C17H15N3O3
Molecular Weight	309.32 g/mol
Synonyms	(E)-N'-(2-Oxo-2,3-dihydro-1H-indol-3-ylidene)-2-(4-methylphenoxy)acetohydrazide; (E)-2-(4-Methylphenoxy)-N'-(2-oxoindolin-3-ylidene)acetohydrazide; (E)-2-(p-Tolyloxy)-N'-(2-oxoindolin-3-ylidene)acetohydrazide; (E)-N-(2-Oxoindolin-3-ylidene)-2-(p-tolyloxy)acetohydrazide; (E)-2-(4-Methylphenoxy)-N'-(2-oxo-2,3-dihydro-1H-indol-3-ylidene)acetohydrazide; (E)-N'-(2-Oxo-1,2-dihydro-3H-indol-3-ylidene)-2-(4-methylphenoxy)acetohydrazide; 125299-00-5; Indolin-3-ylidene acetohydrazide derivative
EINECS	Contact for details

Quality Control

Our (E)-n-(2-Oxoindolin-3-Ylidene)-2-(p-Tolyloxy)Acetohydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.