Description

1H-Pyrazole, 1-(9-Borabicyclo[3.3.1]Non-9-Yl)-3,5-Bis(1,1-Dimethylethy L)-4-Ethyl- is a specialized organoboron reagent, specifically a sterically hindered pyrazole-substituted 9-BBN derivative. This compound matters as a highly selective and efficient ligand or catalyst precursor in advanced organic synthesis, particularly for cross-coupling and hydroboration reactions. It is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise control over molecular architecture.

Application

• Pharmaceutical Intermediate Synthesis: As a key building block or catalyst ligand in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its boron-mediated coupling capabilities.
• Polymer & Materials Science: Acts as a functional monomer or catalyst component for creating specialty polymers with tailored properties.
• Cross-Coupling Catalysis: Serves as a precursor for generating active catalytic species in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.
• Asymmetric Synthesis: Employed in the development of chiral ligands for enantioselective transformations in fine chemical production.
• Hydrofunctionalization Reactions: Utilized in catalytic hydroboration and hydrosilylation processes to install functional groups onto olefins.
• Academic & Industrial R&D: A valuable tool for methodological development in synthetic organic chemistry laboratories.

Basic Information

Product Name	1H-Pyrazole, 1-(9-Borabicyclo[3.3.1]Non-9-Yl)-3,5-Bis(1,1-Dimethylethy L)-4-Ethyl-
CAS No.	125281-23-4
Molecular Formula	C20H35BN2
Molecular Weight	314.32 g/mol
Synonyms	1-(9-Borabicyclo[3.3.1]non-9-yl)-3,5-di-tert-butyl-4-ethylpyrazole; 3,5-Di-tert-butyl-4-ethyl-1-(9-borabicyclo[3.3.1]non-9-yl)-1H-pyrazole; 9-BBN-pyrazole derivative; tert-Butyl substituted BBN-pyrazole; Boron, [3,5-bis(1,1-dimethylethyl)-4-ethyl-1H-pyrazol-1-yl]-9-borabicyclo[3.3.1]non-9-yl]-; 1-(9-BBN)-3,5-di-tert-butyl-4-ethylpyrazole; Ligand precursor L1 (commonly used in catalysis literature).
EINECS	Contact for details

Quality Control

Our production of this high-value organoboron compound adheres to stringent quality protocols. Every batch undergoes comprehensive analysis including NMR (1H, 13C, 11B), HPLC for purity assessment, and elemental analysis to confirm composition. We provide detailed Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with your internal quality management systems. Specifications are designed to meet the exacting requirements of cGMP and ISO 9001 environments for advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive) and easily oxidized; ensure containers are sealed immediately after use to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure (1H, 13C, 11B)
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.