Description

2-Thiazolecarbonitrile, n-Oxide (9Ci) is a specialized heterocyclic building block featuring a nitrile group and an N-oxide moiety on a thiazole ring. This unique molecular architecture makes it a valuable intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients, as well as by academic and industrial chemists exploring new materials and catalysts.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the synthesis of new herbicides, fungicides, and insecticides, leveraging the thiazole scaffold's bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis due to its N-oxide and nitrile functional groups.
• Material Science Research: Employed in the synthesis of advanced organic materials, including liquid crystals and conductive polymers.
• Chemical Biology Probes: Utilized as a building block for designing molecular probes and inhibitors to study enzyme function and biological pathways.

Basic Information

Item	Details
Product Name	2-Thiazolecarbonitrile, n-Oxide (9Ci)
CAS No.	125264-26-8
Molecular Formula	C4H2N2OS
Molecular Weight	126.14 g/mol
Synonyms	2-Cyanothiazole N-Oxide; Thiazole-2-carbonitrile N-Oxide; 2-Cyanothiazole 1-Oxide; 2-Thiazolecarbonitrile 1-Oxide; 2-Thiazolylcarbonitrile N-Oxide; 2-Thiazolecarbonitrile oxide; 125264-26-8 (CAS); Thiazole-2-carbonitrile oxide
EINECS	Contact for details

Quality Control

Our 2-Thiazolecarbonitrile, n-Oxide (9Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.