Description

2-Methyl-5-Tosyl-2,5-Diaza-Bicyclo[2.2.1]Heptane is a sophisticated bicyclic organic compound featuring a tosyl-protected diaza bridgehead structure, serving as a critical chiral building block and intermediate in advanced synthetic chemistry. Its rigid, three-dimensional scaffold is highly valued for imparting specific stereochemical and conformational properties to target molecules, enabling the development of novel pharmaceuticals and agrochemicals. This intermediate is primarily sought by research institutions and industrial R&D departments focused on medicinal chemistry, asymmetric synthesis, and the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of complex drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Asymmetric Catalyst Ligand Precursor: Used to develop novel ligands for transition metal catalysis, enabling enantioselective transformations.
• Agrochemical Research: Serves as a building block for creating new pesticides and herbicides with enhanced efficacy and selectivity.
• Academic & Process Chemistry: Employed in methodological studies and scale-up process development for novel synthetic routes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and proprietary intermediates for clients.

Basic Information

Product Name	2-Methyl-5-Tosyl-2,5-Diaza-Bicyclo[2.2.1]Heptane
CAS No.	125109-58-2
Molecular Formula	C14H20N2O2S
Molecular Weight	280.39 g/mol
Synonyms	2-Methyl-5-(4-methylphenylsulfonyl)-2,5-diazabicyclo[2.2.1]heptane; 2-Methyl-5-tosyl-2,5-diazabicyclo[2.2.1]heptane; 2,5-Diaza-2-methyl-5-(p-tolylsulfonyl)bicyclo[2.2.1]heptane; 2-Methyl-5-(p-toluenesulfonyl)-2,5-diazabicyclo[2.2.1]heptane; N-Methyl-N'-(p-tolylsulfonyl)-1,4-diazabicyclo[2.2.1]heptane; 125109-58-2; Tosyl-protected diazabicycloheptane derivative
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-Tosyl-2,5-Diaza-Bicyclo[2.2.1]Heptane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.