Description

4-Mercaptobutyramidine is a specialized organic compound featuring both a thiol (mercapto) and an amidine functional group. This unique bifunctional structure makes it a valuable intermediate for synthesizing complex molecules in pharmaceutical and agrochemical research. It is particularly sought after by R&D chemists and process development scientists working on novel drug candidates, enzyme inhibitors, and crop protection agents. The compound's reactivity profile allows for selective modifications, enabling the construction of targeted chemical libraries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential protease inhibitors, antiviral agents, and other bioactive molecules.
• Agrochemical Research: Used in developing novel fungicides, herbicides, and plant growth regulators that leverage the thiol reactivity.
• Bioconjugation & Probe Synthesis: The thiol group is utilized for site-specific labeling of proteins, peptides, and other biomolecules for diagnostic and research applications.
• Ligand Synthesis for Catalysis: Serves as a precursor for creating chelating ligands used in homogeneous catalysis and material science.
• Chemical Biology Tool: Employed in studying enzyme mechanisms and designing activity-based probes due to its reactive functional groups.
• Polymer Modification: Can be used to introduce functional handles into polymer backbones for creating advanced materials with specific properties.

Basic Information

Product Name	4-Mercaptobutyramidine
CAS No.	124985-62-2
Molecular Formula	C4H10N2S
Molecular Weight	118.20 g/mol
Synonyms	4-Mercaptobutyramidine; 4-Amidinobutanethiol; 4-Thiolbutyramidine; Butyramidine, 4-mercapto-; 4-Sulfanylbutanimidamide; 4-Mercaptobutyrimidamide; 124985-62-2; NSC 339586
EINECS	Contact for details

Quality Control

Our 4-Mercaptobutyramidine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development purposes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as purity (by HPLC/NMR), identity confirmation, and impurity profiles. We support custom synthesis and can tailor specifications, including chiral purity if required, to meet specific project needs. Certificates of Analysis are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. This product is light-sensitive and easily oxidized. Allow the container to reach room temperature before opening to prevent moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.