Description

(S)-2-o-Benzyl-1-Iodo-3-Butene is a chiral, non-racemic organic intermediate featuring a reactive vinyl iodide functional group. This compound is of significant value in synthetic organic chemistry, particularly for its role in stereoselective carbon-carbon bond-forming reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex, optically active target molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those requiring specific stereochemistry.
• Cross-Coupling Reactions: Serves as an electrophilic partner in palladium-catalyzed cross-coupling reactions, such as the Heck, Suzuki, and Stille couplings, to introduce the butenyl moiety.
• Asymmetric Synthesis: Used in the construction of chiral centers for natural products and fine chemicals, leveraging its pre-existing (S)-configuration.
• Agrochemical Research: Employed in the development of novel pesticides and herbicides where specific stereoisomers are required for optimal biological activity.
• Material Science Precursor: Can act as a monomer or functionalization agent in the development of specialized polymers and advanced materials.

Basic Information

Product Name	(S)-2-o-Benzyl-1-Iodo-3-Butene
CAS No.	124909-04-2
Molecular Formula	C11H13I
Molecular Weight	272.12 g/mol
Synonyms	(S)-1-Iodo-2-(benzyloxy)-3-butene; (S)-2-(Benzyloxy)-1-iodo-3-butene; (S)-2-Benzyloxy-1-iodobut-3-ene; (S)-1-Iodo-3-buten-2-yl benzyl ether; (S)-3-Buten-2-ol, 1-iodo-, benzyl ether
EINECS	Contact for details

Quality Control

Our (S)-2-o-Benzyl-1-Iodo-3-Butene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profiles is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled under an inert atmosphere when appropriate to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.