Description

S-[(2-Guanidino-4-Thiazoyl)Methyl] Isothiourea Hydrochloride Salt is a high-purity, non-natural amino acid derivative and a key synthetic intermediate in advanced pharmaceutical research. This compound is valued for its role in the development of novel therapeutic agents, particularly as a building block for peptidomimetics and enzyme inhibitors. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting enzyme-related pathways.
• Peptidomimetic Research: Used to construct modified peptide backbones that mimic natural peptides but with enhanced stability or bioavailability.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies in the search for new bioactive molecules.
• Bioconjugation: Potential use in creating chemical linkers for antibody-drug conjugates (ADCs) or other targeted therapies.
• Chemical Biology Probes: Employed in the development of tool compounds for studying biological processes and target validation.
• Process Chemistry: Used in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).

Basic Information

Product Name	S-[(2-Guanidino-4-Thiazoyl)Methyl] Isothiourea Hydrochloride Salt
CAS No.	124646-05-5
Molecular Formula	C6H11N5S2 • HCl
Molecular Weight	277.78 g/mol
Synonyms	2-Guanidino-4-[(isothioureido)methyl]thiazole Hydrochloride; (2-Guanidino-4-thiazolyl)methyl Isothiourea Hydrochloride; S-[(2-Guanidino-4-thiazolyl)methyl]isothiourea Monohydrochloride; 4-[(Aminomethanethioyl)amino]methyl]-2-guanidinothiazole Hydrochloride; NSC 339586; CAS 124646-05-5
EINECS	Contact for details

Quality Control

Our S-[(2-Guanidino-4-Thiazoyl)Methyl] Isothiourea Hydrochloride Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.