Description

tert-Butyl 3-[5-(2-Amino-Ethyl)-Thiophen-3-Yl]-Acrylate is a high-value, functionalized thiophene derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate, enabling the construction of complex molecular architectures with tailored electronic and biological properties. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Building block for developing new-generation pesticides and herbicides with enhanced efficacy and selectivity.
• Organic Electronic Materials: Used in the research and development of conductive polymers, organic semiconductors, and OLED materials due to the thiophene moiety.
• Chemical Biology Probes: Serves as a scaffold for creating fluorescent tags or molecular probes to study biological processes.
• Polymer Modification: Acrylate functionality allows for incorporation into polymer backbones to impart specific chemical or physical properties.
• Academic & Contract Research: Essential reagent for methodological development and exploratory chemistry in university and CRO laboratories.

Basic Information

Product Name	tert-Butyl 3-[5-(2-Amino-Ethyl)-Thiophen-3-Yl]-Acrylate
CAS No.	124499-25-8
Molecular Formula	C13H19NO2S
Molecular Weight	253.36 g/mol
Synonyms	tert-Butyl (2E)-3-[5-(2-aminoethyl)-3-thienyl]acrylate; 3-Thiopheneacrylic acid, 5-(2-aminoethyl)-, 1,1-dimethylethyl ester; 5-(2-Aminoethyl)thiophene-3-acrylic acid tert-butyl ester; 2-tert-Butoxycarbonylvinyl-5-(2-aminoethyl)thiophene; tert-Butyl (E)-3-(5-(2-aminoethyl)thiophen-3-yl)acrylate; Acrylic acid, 3-[5-(2-aminoethyl)-3-thienyl]-, 1,1-dimethylethyl ester; (E)-tert-Butyl 3-(5-(2-aminoethyl)thiophen-3-yl)acrylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-[5-(2-Amino-Ethyl)-Thiophen-3-Yl]-Acrylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.