Description

3-(1,2-o-Isopropylidene-Threofuranos-4-Yl)Maleimide is a high-purity, specialized chemical building block used in advanced organic synthesis. This compound is valued for its unique molecular architecture, which serves as a key intermediate in the development of complex bioactive molecules and novel materials. It is primarily sought by research institutions and pharmaceutical companies engaged in carbohydrate chemistry, medicinal chemistry, and the synthesis of nucleoside analogs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleoside analogs and antiviral/antitumor agents.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Carbohydrate Chemistry: Serves as a protected, functionalized sugar derivative for constructing complex oligosaccharides or glycoconjugates.
• Bioconjugation: The maleimide group enables selective coupling with thiols, useful for labeling proteins, peptides, or other biomolecules.
• Polymer Science: Can be incorporated as a monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Academic & Industrial R&D: Employed in exploratory research for developing new chemical entities and advanced materials.

Basic Information

Product Name	3-(1,2-o-Isopropylidene-Threofuranos-4-Yl)Maleimide
CAS No.	124484-34-0
Molecular Formula	C11H13NO5
Molecular Weight	239.22 g/mol
Synonyms	4-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1,2-O-isopropylidene-α-L-threo-pentofuranose; 1-(1,2-O-Isopropylidene-α-L-threofuranosyl)maleimide; 3-(1,2-O-Isopropylidene-α-L-threofuranos-4-yl)-1H-pyrrole-2,5-dione; 3-(1,2-O-Isopropylidene-threofuranos-4-yl)maleimide; 3-(1,2-O-Isopropylidene-α-L-threofuranosyl)maleimide; L-Threofuranose, 4-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1,2-O-(1-methylethylidene)-
EINECS	Contact for details

Quality Control

Our 3-(1,2-o-Isopropylidene-Threofuranos-4-Yl)Maleimide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific research or project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.