Description

Aglepristone is a synthetic steroid compound that acts as a selective progesterone receptor antagonist. This specific pharmacological profile makes it a critical active pharmaceutical ingredient (API) for targeted veterinary and research applications. It is primarily utilized in the development of therapeutic agents for hormone-dependent conditions. Professional buyers in the pharmaceutical, veterinary medicine, and advanced life science research sectors source this compound for its precise biological activity.

Application

• Veterinary Pharmaceutical API: Core active ingredient in medications for managing progesterone-related conditions in animals, such as pregnancy termination or pyometra in dogs.
• Endocrinology Research: Used as a key tool compound in laboratory studies to investigate progesterone receptor signaling pathways and their physiological roles.
• Drug Discovery & Development: Serves as a reference standard or lead compound in pharmaceutical R&D for novel antiprogestins.
• Veterinary Reproduction Management: Employed in clinical settings for the medical management of mismating and the induction of parturition under veterinary supervision.
• Biochemical Assay Standard: Used to calibrate assays and validate methods for detecting progesterone receptor activity in diagnostic or research kits.

Basic Information

Product Name	Aglepristone
CAS No.	124478-60-0
Molecular Formula	C₂₉H₃₅NO₄
Molecular Weight	449.60 g/mol
Synonyms	RU 46534; RU-46534; 11β-[4-(Dimethylamino)phenyl]-17β-hydroxy-17α-(3-hydroxypropyl)-13α-estra-4,9-dien-3-one; 11β-[4-(Dimethylamino)phenyl]-17α-(3-hydroxypropyl)-17β-hydroxy-13α-estra-4,9-dien-3-one; Aglépristone; Alizin (Veterinary Trade Name)
EINECS	Contact for details

Quality Control

Our Aglepristone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets high-grade pharmaceutical standards. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.