Description

1-Naphthol-D7 is a deuterium-labeled derivative of 1-naphthol, a key aromatic compound used extensively as an analytical standard and internal tracer. This high-purity isotopologue is essential for ensuring accuracy and reliability in quantitative mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy. It is primarily required by researchers and quality control laboratories in the pharmaceutical, agrochemical, and environmental testing sectors for method development, validation, and precise metabolite tracking.

Application

• Internal Standard for LC-MS/MS: Used as a quantitative reference standard in liquid chromatography-tandem mass spectrometry for analyzing 1-naphthol and related metabolites in complex biological and environmental matrices.
• Metabolite Tracing & Pharmacokinetics: Enables precise tracking of drug metabolism and distribution studies in pharmaceutical R&D, leveraging its distinct mass signature.
• NMR Spectroscopy Solvent: Serves as a deuterated solvent shift reference or internal standard in nuclear magnetic resonance experiments.
• Environmental Analysis: Acts as a labeled standard for monitoring the degradation of naphthalene-based pesticides and industrial pollutants in soil and water samples.
• Isotope Dilution Mass Spectrometry (IDMS): Critical for achieving high-accuracy measurements in definitive analytical methods requiring minimal uncertainty.
• Chemical Synthesis Research: Employed as a labeled starting material or intermediate in the synthesis of more complex deuterated compounds for mechanistic studies.

Basic Information

Product Name	1-Naphthol-D7
CAS No.	124251-84-9
Molecular Formula	C10D7HO
Molecular Weight	159.23 g/mol
Synonyms	1-Naphthalenol-D7; 1-Hydroxynaphthalene-D7; α-Naphthol-D7; Naphth-1-ol-D7; [D7]-1-Naphthol; Deuterated 1-Naphthol; 1-Naphthol (phenyl-D5, hydroxy-D2); Perdeuterated 1-Naphthol (partial)
EINECS	Contact for details

Quality Control

Every batch of 1-Naphthol-D7 is manufactured and tested under strict quality management protocols to ensure exceptional isotopic purity and chemical integrity. Our products undergo rigorous quality testing, including advanced spectroscopic and chromatographic methods, to ensure compliance with industry standards for labeled compounds. Certificates of Analysis (COA) detailing isotopic enrichment (D%), chemical purity, and analytical results are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D%)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.