Description

Dl-Cysteine (3,3-D2) CAS NO 124051-54-3 is a deuterium-labeled isotopologue of the amino acid DL-cysteine, where two hydrogen atoms at the 3-position are replaced with deuterium. This stable isotope labeling is critical for advanced research applications requiring precise molecular tracking and analysis. It is an essential material for scientists and manufacturers in the fields of pharmaceutical development, metabolic research, and analytical chemistry who require high-purity, isotopically defined building blocks.

Application

• Pharmaceutical Research & Development: Used as a stable isotope-labeled internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the quantitative bioanalysis of cysteine-containing drugs and metabolites.
• Metabolic Pathway Tracing: Serves as a crucial tracer in metabolic flux analysis and pharmacokinetic studies to elucidate the pathways and turnover rates of sulfur-containing compounds in biological systems.
• Proteomics and Biomarker Discovery: Employed in isotope-coded affinity tag (ICAT) and other labeling techniques for comparative quantitative proteomics to identify and quantify proteins in complex mixtures.
• NMR Spectroscopy: Acts as a valuable tool in Nuclear Magnetic Resonance (NMR) spectroscopy, where deuterium labeling simplifies spectra and allows for detailed structural and dynamic studies of peptides and proteins.
• Chemical Synthesis Intermediates: Utilized as a specialized, labeled starting material or intermediate in the synthesis of deuterated peptides, drug candidates, and other bioactive molecules for research purposes.

Basic Information

Product Name	Dl-Cysteine (3,3-D2)
CAS No.	124051-54-3
Molecular Formula	C3H5D2NO2S
Molecular Weight	123.16 g/mol (for monoisotopic)
Synonyms	(±)-3,3-Dideutero-2-amino-3-mercaptopropanoic acid; DL-Cysteine-3,3-d2; DL-3,3-Dideuterocysteine; (R,S)-Cysteine-3,3-d2; 2-Amino-3-mercaptopropanoic-3,3-d2 acid; DL-2-Amino-3-mercaptopropionic-3,3-d2 acid; (±)-Cysteine-3,3-d2
EINECS	Contact for details

Quality Control

Every batch of our Dl-Cysteine (3,3-D2) is produced and analyzed under strict quality management protocols. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as isotopic purity (D-enrichment), chemical purity, and specific tests. Our commitment ensures the material meets the stringent requirements for research and development applications. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.